TORONTO METROPOLITAN UNIVERSITY

Course Outline (W2024)

BME674: Biomedical Instrumentation

Instructor(s)Dr. M. Ali Tavallaei [Coordinator]
Office: ENG466
Phone: (416) 979-5000 x 556078
Email: ali.tavallaei@torontomu.ca
Office Hours: Mondays 1-2 pm
Calendar DescriptionThis course deals with the application and design of medical instrumentation systems for which the source of the signals is living tissue or energy applied to living tissues. The major emphasis will be on, transduction principles, sensors, detectors, electronic signal conditioning and processing techniques, and electrical safety standards for medical instrumentation. Some of the major topics include: sensors and transducers - e.g. displacement, resistive, inductive, capacitive, piezoelectric, temperature, radiation thermometry, optical etc.; special-purpose amplification and signal processing techniques; ECG-EMG-EEG biopotential electrodes and amplifiers; non-invasive blood pressure, flow-rate and volume sensing and measurement techniques; respiratory plethysmography; electrochemical biosensors and laboratory instruments; medical imaging systems; and designs for electrical safety. Important instrumentation design concepts are illustrated through design labs, a final design project, and use of circuit simulation tools.
PrerequisitesBLG 601, BLG 701, BME 506, BME 538, CEN 199
Antirequisites

None

CorerequisitesBME 532
Compulsory Text(s):
  1. Medical Instrumentation: Application and Design, John G. Webster, 5 th edition, John Wiley and Sons, Inc, 2020.
Reference Text(s):
  1. Bioinstrumentation, John G. Webster (Editor), John Wiley & Sons, Inc, 2004.
Learning Objectives (Indicators)  

At the end of this course, the successful student will be able to:

  1. Demonstrate in-depth understanding of key concepts and principles of biomedical instrumentation. Demonstrate, integrate and apply specialized inter-disciplinary engineering principles for design and development of biomedical instrumentation systems. (1d)
  2. Describe differences between methods and components and then perform a specific method and component integration in a hypothetical design situation. Subsequently integrate the generated ideas into a design plan for a simple biomedical instrumentation system, generating ideas creatively or ad-hoc where established methods fail. (4b)
  3. Describe iterative process models of design and modify, improve or elaborate a design state using feedback (from expert or system performance results) to achieve specified targets. (4c)
  4. Demonstrate the ability to use the knowledge on biomedical instrumentation and measurement equipment for obtaining valid data. (5a)
  5. Produce formal lab and project reports using appropriate format, grammar, and citation styles for technical and non-technical audiences. Cites evidence (e.g. data sheets, literature) to support the design considerations. (7a)
  6. Know the role of the biomedical engineer in society. Including responsibility for protecting, specifically, patient safety, and, generally, the broader public interest. (8b)
  7. Describe interactions between biomedical instrumentation system design and economic and environmental factors. (9b)
  8. Demonstrate the ability to source and use technical information related to biomedical instrumentation. (12a)

NOTE:Numbers in parentheses refer to the graduate attributes required by the Canadian Engineering Accreditation Board (CEAB).

Course Organization

3.0 hours of lecture per week for 13 weeks
2.0 hours of lab per week for 12 weeks
0.0 hours of tutorial per week for 12 weeks

Teaching AssistantsSina Keshavarz: mkeshavarz@torontomu.ca
 Mohammad Khoobani: mohammad.khoobani@torontomu.ca
 Robnier Reyes Perez: rreyespe@torontomu.ca
Course Evaluation
Theory
Midterm Exam 25 %
Final Exam 45 %
Laboratory
Labs 15 %
Project 15 %
TOTAL:100 %

Note: In order for a student to pass a course, a minimum overall course mark of 50% must be obtained. In addition, for courses that have both "Theory and Laboratory" components, the student must pass the Laboratory and Theory portions separately by achieving a minimum of 50% in the combined Laboratory components and 50% in the combined Theory components. Please refer to the "Course Evaluation" section above for details on the Theory and Laboratory components (if applicable).


ExaminationsThe midterm exam is in Week 6, two hours, closed book (covers up to the prior week of the midterm exam), formula sheet permitted.
 Final exam, during the exam period, three hours, closed book (covers all material), formula sheet permitted.
Other Evaluation InformationNone
Teaching MethodsIn-person lectures, laboratories, and pre-recorded videos.
Other InformationMajor Design Lab Project
 In the course project, students will design a biomedical signal acquisition and processing system based on LabView-Microprocessor/Microcontroller interface. The project is open-ended, and the student can choose the measurand, appropriate transduction principle, components, and quantification approaches for their design while adhering to the general design process for medical instrumentation. The project groups will be the same as the lab groups. The last four weeks of the lab sessions will be used for the project work. The students can do the groundwork for the project from the start of the course and will submit a proposal outlining their design plan with proper justifications of their design considerations by Week 8 and should get it evaluated and approved by the Instructor/TA. From week 9 to 13, students will engage in the implementation phase. During this phase, students will consult with the instructor/TA to discuss their weekly progress and incorporate feedback to improve their design. In the last week of their respective lab sessions, the students will demonstrate their projects to the Instructor/TA and submit a report with the following sections: problem definition, literature survey (pertaining to the justification for their design), methodology, implementation details, and performance analysis. The project reports should be written in a manner that the main theme of the project can be understood by a non-technical reader. Individual student contributions are to be highlighted with consent from all the group members. The project will be evaluated based on the proposed design considerations incorporating the following four factors: (i) Signal, (ii) Medical, (iii) Environmental, and (iv) Economic (Refer to Figure 1.8 in the Text Book for more details). The report should clearly justify the design choices with respect to the above four factors.

Course Content

Week

Hours

Chapters /
Section

Topic, description

1

3

Chapter 1 and 14 Sections 1.1-1.10, 1.25-1.27 14.1-14.9

Basic Concepts of Medical Instruments & Electrical Safety


2-3

6

Chapter 1 Sections 1.11-1.24

Amplifiers and Signal Processing
 


4-6

6

Chapter 2 and 10 Sections 2.1-2.14, 10.1-10.2 and 10.9

Basic Sensors & Principles
 


7-8

3

Chapter 3

Microcontrollers in Medical Instrumentation
 


8-10

9

Chapter 4-6 Sections 4.1-4.2, 5.1-5.8 6.1-6.7, 6.10 (Self Study Sections 4.3-4.9)

Midterm Test, The Origin of Biopotentials, Electrodes, and Amplifiers


11-12

6

Chapters 7-9 and 11, Sections 7.1 7.9, 7.10 7.13, 8.4,8.5-8.7,8.8 9.7, 11.1, 11.4

Applications: Measurements of Blood Pressure Flow Volume and Respiratory System. Overview of Laboratory Instrumentation
 


12-13

4

Chapter 12 Sections 12.5, 12.7, 12.8, 12.12

Medical Imaging: Radiography Ultrasonography Computed Tomography Magnetic Resonance Imaging
 


Laboratory(L)/Tutorials(T)/Activity(A) Schedule

Week

L/T/A

Description

1

L

Design Lab 0: Introduction & Review

2-4

L

Design Lab 1: Amplifiers and Signal Processing

5-6

L

Design Lab 2: Sensors

7-9

L

Design Lab3: ECG - Measurement and Monitoring

9-13

L

Project (Major Design Lab): Biomedical Signal Acquisition - Microcontroller-LabviewInterface-Based System.

University Policies & Important Information

Students are reminded that they are required to adhere to all relevant university policies found in their online course shell in D2L and/or on the Senate website

Refer to the Departmental FAQ page for furhter information on common questions.

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