| Instructor(s) | Dr. Owais Khan [Coordinator] Office: ENG328 Phone: (416) 979-5000 x 556096 Email: owaiskhan@torontomu.ca Office Hours: | ||||||||||||
| Calendar Description | Tissue engineering approach for augmentation or replacement of compromised tissue function in nerve, microvessels, skin and cartilage. Integrative exploration of the use of three-dimensional polymeric scaffolds and drug delivery vehicles, and gene therapy and cellular engineering for functional repair of injured tissues. | ||||||||||||
| Prerequisites | BLG 601 and BLG 701 | ||||||||||||
| Antirequisites | None | ||||||||||||
| Corerequisites | None | ||||||||||||
| Compulsory Text(s): |
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| Reference Text(s): |
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| Learning Objectives (Indicators) | At the end of this course, the successful student will be able to:
NOTE:Numbers in parentheses refer to the graduate attributes required by the Canadian Engineering Accreditation Board (CEAB). | ||||||||||||
| Course Organization | 3.0 hours of lecture per week for 13 weeks | ||||||||||||
| Teaching Assistants | Lab Teaching Assistants: ================== Aayush Chakravartti (aayush.chakravartti@torontomu.ca) Dana Almasri (dmasri1@torontomu.ca) Tutorial Teaching Assistants: ===================== Quentin Currier-Mortisugu (qcurriermoritsugu@torontomu.ca) Abdul Malek Aziz (abdulmalek.azouz@torontomu.ca). | ||||||||||||
| Course Evaluation |
Note: In order for a student to pass a course, a minimum overall course mark of 50% must be obtained. In addition, for courses that have both "Theory and Laboratory" components, the student must pass the Laboratory and Theory portions separately by achieving a minimum of 50% in the combined Laboratory components and 50% in the combined Theory components. Please refer to the "Course Evaluation" section above for details on the Theory and Laboratory components (if applicable). | ||||||||||||
| Examinations | Midterm exam in Week 7, two hours (covers Weeks 1-6) Final exam, during exam period, three hours (covers Weeks 1-13). | ||||||||||||
| Other Evaluation Information | Important Notes: =============== Any late submission of laboratory report (without justifiable reasons and advanced notice to the instructor/TA) will result in a mark deduction as below: a. A zero mark will be awarded for handing in no lab report b. 10% deduction if submitted within 24 hours late c. 20% deduction per day past deadline | ||||||||||||
| Teaching Methods | Email Policy ============ In accordance with the Policy on Student E-mail Accounts (Policy 157), Toronto Metropolitan University (TMU) requires that any electronic communication by students to TMU faculty or staff be sent from their official university email account. Teaching Methods ================ Please refer to BME 703 Tissue Engineering Laboratory Manual for additional details of each lab session. All lab reports must have the standard cover page, to be signed by the student prior to submission, which can be completed and printed from the Department website at: https://www.ecb.torontomu.ca/guides/Standard_Cover_Page_Assignments.pdf | ||||||||||||
| Other Information | None | ||||||||||||
Week | Hours | Chapters / | Topic, description |
|---|---|---|---|
1 | 3 | Notes | Introduction to Tissue Engineering |
2 | 3 | Chapter 1 Sections 1.1-1.3 and Notes | Cellular Therapies |
3 | 3 | Chapter 2 Sections 2.1-2.3 and Notes | Tissue Organization |
4 | 3 | Chapter 5 and Notes | Stem Cells |
5 | 3 | Chapter 3, 4 and Notes | Tissue Dynamics and Morphogenesis |
6 | 3 | Chapters 6,7 Sections 6.1-6.5, 7.1-7.4 and Notes | Cell Differentiation |
7 | 3 | Midterm | ------------- MIDTERM EXAM------------- |
8 | 3 | Chapters 6,7 Sections 6.1-6.5, 7.1-7.4 and Notes | Cellular Fate Processes I |
9 | 3 | Chapters 6,7 Sections 6.1-6.5, 7.1-7.4 and Notes | Cellular Fate Process II |
10 | 3 | Chapter 10 and Notes | Cell and Tissue Culture |
11 | 3 | Chapter 13 and Notes | Scaling up for Ex-Vivo Cultivation |
12 | 3 | Notes | Ethics, IP and Regulatory Affairs |
13 | 3 | Notes | Review |
Week | L/T/A | Description |
|---|---|---|
2 | Tutorial 1 | Tutorial 1 |
3 | Lab 1 Modules | Lab Safety; Biosafety; Pipetting; Microscopy |
4 | Tutorial 2 | Tutorial 2 |
5 | Lab 2 Modules | Membranes |
6 | Tutorial 3 | Tutorial 3 |
7 | Lab 3 Modules | Cytoskeleton |
8 | Tutorial 4 | Tutorial 4 |
9 | Lab 4 Modules | Phagocytosis |
10 | Tutorial 5 | Tutorial 5 |
11 | Lab 5 Modules | Growth of Cells |
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