Instructor(s) | Dr. Owais Khan [Coordinator] Office: ENG328 Phone: (416) 979-5000 x 556096 Email: owaiskhan@torontomu.ca Office Hours: | Calendar Description | Tissue engineering approach for augmentation or replacement of compromised tissue function in nerve, microvessels, skin and cartilage. Integrative exploration of the use of three-dimensional polymeric scaffolds and drug delivery vehicles, and gene therapy and cellular engineering for functional repair of injured tissues. | ||||||||||
Prerequisites | BLG 601 and BLG 701 | ||||||||||||
Antirequisites | None | ||||||||||||
Corerequisites | None | ||||||||||||
Compulsory Text(s): |
| ||||||||||||
Reference Text(s): |
| ||||||||||||
Learning Objectives (Indicators) | At the end of this course, the successful student will be able to:
NOTE:Numbers in parentheses refer to the graduate attributes required by the Canadian Engineering Accreditation Board (CEAB). | ||||||||||||
Course Organization | 3.0 hours of lecture per week for 13 weeks | ||||||||||||
Teaching Assistants | Lab TAs: --------- 1) Peter Zastawny (pzastawny@torontomu.ca) 2) Dana Almasri (dmasri1@torontomu.ca) Tutorial TAs: ------------ 3) Parmiss Kiani (pkiani@torontomu.ca) 4) Seham Al Abdul Wahid (salabdulwahid@torontomu.ca) | ||||||||||||
Course Evaluation |
Note: In order for a student to pass a course, a minimum overall course mark of 50% must be obtained. In addition, for courses that have both "Theory and Laboratory" components, the student must pass the Laboratory and Theory portions separately by achieving a minimum of 50% in the combined Laboratory components and 50% in the combined Theory components. Please refer to the "Course Evaluation" section above for details on the Theory and Laboratory components (if applicable). | ||||||||||||
Examinations | Midterm exam in Week 7, two hours (covers Weeks 1-6) Final exam, during exam period, three hours (covers Weeks 1-13). | ||||||||||||
Other Evaluation Information | Important Notes: =============== Any late submission of laboratory report (without justifiable reasons and advanced notice to the instructor/TA) will result in a mark deduction as below: a. A zero mark will be awarded for handing in no lab report b. 10% deduction if submitted within 24 hours late c. 20% deduction per day past deadline Exams 1. The midterm and final exams will include questions that include of problem solving nature as well as short-answer and definition-based questions. 2. Students must receive a grade of at least 35% on the final exam in order to pass the course. | ||||||||||||
Teaching Methods | Email Policy ============ In accordance with the Policy on Student E-mail Accounts (Policy 157), Toronto Metropolitan University (TMU) requires that any electronic communication by students to TMU faculty or staff be sent from their official university email account. Teaching Methods ================ Lectures will be held on Mondays from 3pm to 6pm. Please refer to BME 703 Tissue Engineering Laboratory Manual for additional details of each lab session. All lab reports must have the standard cover page, to be signed by the student prior to submission, which can be completed and printed from the Department website at: https://www.ecb.torontomu.ca/guides/Standard_Cover_Page_Assignments.pdf | ||||||||||||
Other Information | None |
Week | Hours | Chapters / | Topic, description |
---|---|---|---|
1 | 3 | Notes | Introduction to Tissue Engineering |
2 | 3 | Chapter 1 Sections 1.1-1.3 and Notes | Cellular Therapies |
3 | 3 | Chapter 2 Sections 2.1-2.3 and Notes | Tissue Organization |
4 | 3 | Chapter 5 and Notes | Stem Cells |
5 | 3 | Chapter 3, 4 and Notes | Tissue Dynamics and Morphogenesis |
6 | 3 | Chapters 6,7 Sections 6.1-6.5, 7.1-7.4 and Notes | Cell Differentiation |
7 | 3 | Midterm | ------------- MIDTERM EXAM------------- |
8 | 3 | Chapters 6,7 Sections 6.1-6.5, 7.1-7.4 and Notes | Cellular Fate Processes I |
9 | 3 | Chapters 6,7 Sections 6.1-6.5, 7.1-7.4 and Notes | Cellular Fate Process II |
10 | 3 | Chapter 10 and Notes | Cell and Tissue Culture |
11 | 3 | Chapter 13 and Notes | Scaling up for Ex-Vivo Cultivation |
12 | 3 | Notes | IP and Regulatory Affairs |
13 | 3 | Notes | Review |
Week | L/T/A | Description |
---|---|---|
2 | Tutorial 1 | Tutorial 1 |
3 | Lab 1 Modules | Lab Safety; Biosafety; Pipetting; Microscopy |
4 | Tutorial 2 | Tutorial 2 |
5 | Lab 2 Modules | Membranes |
6 | Tutorial 3 | Tutorial 3 |
7 | Lab 3 Modules | Cytoskeleton |
8 | Tutorial 4 | Tutorial 4 |
9 | Lab 4 Modules | Phagocytosis |
10 | Tutorial 5 | Tutorial 5 |
11 | Lab 5 Modules | Growth of Cells |
Students are reminded that they are required to adhere to all relevant university policies found in their online course shell in D2L and/or on the Senate website
You can submit an Academic Consideration Request when an extenuating circumstance has occurred that has significantly impacted your ability to fulfill an academic requirement. You may always visit the Senate website and select the blue radio button on the top right hand side entitled: Academic Consideration Request (ACR) to submit this request.
For Extenuating Circumstances, Policy 167: Academic Consideration allows for a once per semester ACR request without supporting documentation if the absence is less than 3 days in duration and is not for a final exam/final assessment. Absences more than 3 days in duration and those that involve a final exam/final assessment, require documentation. Students must notify their instructor once a request for academic consideration is submitted. See Senate Policy 167: Academic Consideration.
Academic Accommodation Support (AAS) is the university's disability services office. AAS works directly with incoming and returning students looking for help with their academic accommodations. AAS works with any student who requires academic accommodation regardless of program or course load.
Academic Accommodations (for students with disabilities) and Academic Consideration (for students faced with extenuating circumstances that can include short-term health issues) are governed by two different university policies. Learn more about Academic Accommodations versus Academic Consideration and how to access each.
At Toronto Metropolitan University, we recognize that things can come up throughout the term that may interfere with a student’s ability to succeed in their coursework. These circumstances are outside of one’s control and can have a serious impact on physical and mental well-being. Seeking help can be a challenge, especially in those times of crisis.
If you are experiencing a mental health crisis, please call 911 and go to the nearest hospital emergency room. You can also access these outside resources at anytime:
If non-crisis support is needed, you can access these campus resources:
We encourage all Toronto Metropolitan University community members to access available resources to ensure support is reachable. You can find more resources available through the Toronto Metropolitan University Mental Health and Wellbeing website.