RYERSON UNIVERSITY

Course Outline (F2019)

BME777: Emerging Topics in Biomedical Engineering

Instructor(s)Victor Yang [Coordinator]
Office: EPH400L
Phone: (416) 979-5000 x 2143
Email: yangv@ryerson.ca
Office Hours: TBA
Calendar DescriptionThis course will introduce students to emerging areas in biomedical engineering with specific topics geared towards current trends. The course is structured to be a technical elective i.e., the content may change from year to year depending on the specific topics covered in the course and may be taught by one or more instructors. Students may be required to undertake a major project.
PrerequisitesBLG 601, BLG 701, BME 406, BME 423, BME 501, BME 506, BME 516, BME 632, BME 639, BME 674, EES 612, and MTH 410
Antirequisites

None

Corerequisites

None

Compulsory Text(s):
  1. Joseph D. Bronzino, Medical Devices and Systems, CRC Press, 2006. International Standard Book Number-10: 0-8493-2122-0/International Standard Book Number-13: 978-0-8493-2122-1
Reference Text(s):
  1. Valery Tuchin, Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnosis, SPIE, 2007. International Standard Book Number-10: 0-8194-6433-3/Internati0onal Standard Book Number-13: 978-0-8194-6433-
Learning Objectives (Indicators)  

At the end of this course, the successful student will be able to:

  1. Demonstrate fundamental knowledge on light interaction with biological tissue. (1d)
  2. Perform simple photon propagation simulation using Monte Carlo techniques. (4c)
  3. Demonstrate knowledge on Fourier transform and image processing analysis tools. (5a)
  4. Displays awareness on economic and social risks involved in medical device design. (11b)
  5. Demonstrate skills to source and use information from literature. (12b)

NOTE:Numbers in parentheses refer to the graduate attributes required by the Canadian Engineering Accreditation Board (CEAB).

Course Organization

3.0 hours of lecture per week for 13 weeks
2.0 hours of lab/tutorial per week for 12 weeks

Teaching AssistantsAndrew - andrew.marques@ryerson.ca
 Rob - rreyespe@ryerson.ca
Course Evaluation
Theory
Midterm Exam 25 %
Final Exam 45 %
Laboratory
Labs 15 %
Project 15 %
TOTAL:100 %

Note: In order for a student to pass a course with "Theory and Laboratory" components, in addition to earning a minimum overall course mark of 50%, the student must pass the Laboratory and Theory portions separately by achieving a minimum of 50% in the combined Laboratory components and 50% in the combined Theory components. Please refer to the "Course Evaluation" section for details on the Theory and Laboratory components.


ExaminationsMidterm exam in Week 7, closed book (covers Weeks 1-6).
 Final exam, during exam period, closed book (covers Weeks 1-13).
Other Evaluation InformationLabs: TA(s) will be available only during the scheduled Lab sessions for consultations and evaluation of demos.
 
 Project: From week 7-13, students will perform design feasibility of a Biophotonic Medical Device. Details of project requirements/report format will be discussed in the class.
Other InformationNone

Course Content

Week

Hours

Chapters /
Section

Topic, description

1

3

-

Introduction, example of medical device design and development in
 biophotonics.


2

3

-

Monte Carlo simulation of photon propagation in biological tissue


3

3

-

Tour of Device Development Lab at Sunnybrook Research Institute


4

3

-

Optical coherence tomography – 1 (geometric optics and Gaussian beam)


5

3

-

Optical coherence tomography – 2 (interferometry and Fourier transform)


6

3

-

Optical coherence tomography – 3 (signal intensity and phase)


7

3

-

Mid-term Exam


8

2

-

Magnetic Resonance Imaging introduction


9

3

-

Course Project: Brainstorming


10

3

-

Brain Tumor Fluorescence and PhotoDynamic Therapy (1)


11

3

-

Brain Tumor Fluorescence and PhotoDynamic Therapy (2)


12

3

-

Tour of Biophotonics Bioengineering Lab (BBL) for Surgical Navigation


13

3

-

Optical coherence tomography (hands-on scanning) at BBL


Laboratory/Tutorials/Activity Schedule

Week

Lab

Description

1-2

Lab 0

MATLAB refresher (unmarked)

3-4

Lab 1

Image Analysis using MATLAB (5%)

5-6

Lab 2

Fourier Analysis of Optical Coherence Tomography (5%)

7-8

Lab 3

Photon Propagation Simulation in Biological Tissue (5%)

9-12

Lab4, 5

Project (15%)

Policies & Important Information:

  1. Students are required to obtain and maintain a Ryerson e-mail account for timely communications between the instructor and the students;
  2. Any changes in the course outline, test dates, marking or evaluation will be discussed in class prior to being implemented;
  3. Assignments, projects, reports and other deadline-bound course assessment components handed in past the due date will receive a mark of ZERO, unless otherwise stated. Marking information will be made available at the time when such course assessment components are announced.
  4. Refer to our Departmental FAQ page for information on common questions and issues at the following link: https://www.ee.ryerson.ca/guides/Student.Academic.FAQ.html.

Missed Classes and/or Evaluations

When possible, students are required to inform their instructors of any situation which arises during the semester which may have an adverse effect upon their academic performance, and must request any consideration and accommodation according to the relevant policies as far in advance as possible. Failure to do so may jeopardize any academic appeals.

  1. Health certificates - If a student misses the deadline for submitting an assignment, or the date of an exam or other evaluation component for health reasons, they should notify their instructor as soon as possible, and submit a Ryerson Student Health Certificate AND an Academic Consideration Request form within 3 working days of the missed date. Both documents are available at https://www.ryerson.ca/senate/forms/medical.pdf.. If you are a full-time or part-time degree student, then you submit your forms to your own program department or school;
  2. Religious, Aboriginal and Spiritual observance - If a student needs accommodation because of religious, Aboriginal or spiritual observance, they must submit a Request for Accommodation of Student Religious, Aboriginal and Spiritual Observance AND an Academic Consideration Request form within the first 2 weeks of the class or, for a final examination, within 2 weeks of the posting of the examination schedule. If the requested absence occurs within the first 2 weeks of classes, or the dates are not known well in advance as they are linked to other conditions, these forms should be submitted with as much lead time as possible in advance of the absence. Both documents are available at www.ryerson.ca/senate/forms/relobservforminstr.pdf. If you are a full-time or part-time degree student, then you submit the forms to your own program department or school;
  3. Academic Accommodation Support - Before the first graded work is due, students registered with the Academic Accommodation Support office (AAS - www.ryerson.ca/studentlearningsupport/academic-accommodation-support) should provide their instructors with an Academic Accommodation letter that describes their academic accommodation plan.

Academic Integrity

Ryerson's Policy 60 (the Academic Integrity policy) applies to all students at the University. Forms of academic misconduct include plagiarism, cheating, supplying false information to the University, and other acts. The most common form of academic misconduct is plagiarism - a serious academic offence, with potentially severe penalties and other consequences. It is expected, therefore, that all examinations and work submitted for evaluation and course credit will be the product of each student's individual effort (or an authorized group of students). Submitting the same work for credit to more than one course, without instructor approval, can also be considered a form of plagiarism.

Suspicions of academic misconduct may be referred to the Academic Integrity Office (AIO). Students who are found to have committed academic misconduct will have a Disciplinary Notation (DN) placed on their academic record (not on their transcript) and will normally be assigned one or more of the following penalties:

  1. A grade reduction for the work, ranging up to an including a zero on the work (minimum penalty for graduate work is a zero on the work);
  2. A grade reduction in the course greater than a zero on the work. (Note that this penalty can only be applied to course components worth 10% or less, and any additional penalty cannot exceed 10% of the final course grade. Students must be given prior notice that such a penalty will be assigned (e.g. in the course outline or on the assignment handout);
  3. An F in the course;
  4. More serious penalties up to and including expulsion from the University.

The unauthorized use of intellectual property of others, including your professor, for distribution, sale, or profit is expressly prohibited, in accordance with Policy 60 (Sections 2.8 and 2.10). Intellectual property includes, but is not limited to:

  1. Slides
  2. Lecture notes
  3. Presentation materials used in and outside of class
  4. Lab manuals
  5. Course packs
  6. Exams

For more detailed information on these issues, please refer to the Academic Integrity policy(https://www.ryerson.ca/senate/policies/pol60.pdf) and to the Academic Integrity Office website (https://www.ryerson.ca/academicintegrity/).

Important Resources Available at Ryerson

  1. The Library (https://library.ryerson.ca/) provides research workshops and individual assistance. Inquire at the Reference Desk on the second floor of the library, or go to library.ryerson.ca/guides/workshops
  2. Student Learning Support(https://www.ryerson.ca/studentlearningsupport) offers group-based and individual help with writing, math, study skills and transition support, and other issues.