| Instructor(s) | Dr. Virgilio Valente [Coordinator] Office: ENG450 Phone: (416) 979-5000 x 553728 Email: vvalente@torontomu.ca Office Hours: Tue 1pm-3pm (weeks 2-13) | Calendar Description | Biophysical and chemical principles of biomedical microelectromechanical systems (bioMEMS) for the measurement of biological phenomena and clinical applications. micro-and nano-scale devices for the manipulation of cells and biomolecules. Topics include solid-state transducers, optical transducers, electrochemical transducers, biomedical microelectronics, microfluidics, and hybrid integration of microfabrication technology. | ||||||||||||
| Prerequisites | BME 423 and BME 674 and BME 634 | ||||||||||||||
| Antirequisites | None | ||||||||||||||
| Corerequisites | None | ||||||||||||||
| Compulsory Text(s): |
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| Reference Text(s): |
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| Learning Objectives (Indicators) | At the end of this course, the successful student will be able to:
NOTE:Numbers in parentheses refer to the graduate attributes required by the Canadian Engineering Accreditation Board (CEAB). | ||||||||||||||
| Course Organization | 3.0 hours of lecture per week for 13 weeks | ||||||||||||||
| Teaching Assistants | Sima Darbasi (sima.darbasi@torontomu.ca) Irene Miah (irene.miah@torontomu.ca) | ||||||||||||||
| Course Evaluation |
Note: In order for a student to pass a course, a minimum overall course mark of 50% must be obtained. In addition, for courses that have both "Theory and Laboratory" components, the student must pass the Laboratory and Theory portions separately by achieving a minimum of 50% in the combined Laboratory components and 50% in the combined Theory components. Please refer to the "Course Evaluation" section above for details on the Theory and Laboratory components (if applicable). | ||||||||||||||
| Examinations | Midterm exam will be held in Week 7 of the course on Mar 1 at 11am, lasting for 2 hours, closed book and will cover all material from Weeks 1-6. Final exam during exam period will be three hours, closed-book and will cover all material from Weeks 8-11. | ||||||||||||||
| Other Evaluation Information | Labs will start in week 3. All labs will be related to the design and simulation of bioMEMS components/devices using the software package of Coventorware. The laboratory manuals will be posted on course shell on D2L. The introductory lab will be worth 5%. Labs 1 and 2 will worth 7.5% each. Course Project: Students will complete a course project on a topic of their choosing. Students will work in groups of 4 members (where applicable). Groups must be formed and group topic selected by week 4 of the term and must be approved by the course instructor (topics entered in the provided spreadsheet by 5pm Friday week 4). Details of the term project will be given during class and posted on the BME804 course shell. Project assessment: 1 - Project description due in week 10 in D2L (30%) 2 - Final presentations: Each group will present their course project in a 30-min presentation. Each member of the group must present (approx 7-8 min each). (70%) | ||||||||||||||
| Other Information | Lectures: Friday 11:00 AM - 2:00 PM, DSQ12 Lectures in general consist of: - Lecture material (course topics, examples etc.) - Group activities (discussions, project work) - Offline coursework (reading material, assignments, watch prerecoded videos (where applicable), self-organized group meetings etc.) | ||||||||||||||
Week | Hours | Chapters / | Topic, description |
|---|---|---|---|
1 | 3 | Lecture Topic 1: Introduction to MEMS and BioMEMS. Introduction to MEMS and their applications. | |
2 | 3 | Lecture Topic 2: Silicon Microfabrication Part I. Mask creation, silicon wafer preparation, photolithography, photoresist (positive or negative), UV exposure and development, etching methods, resist stripping. | |
3 | 3 | Lecture Topic 3 : Silicon Microfabrication Part II. Thin films, thin film processes, deposition, micromachining, bonding. | |
4 | 3 | Lecture Topic 4: Soft Fabrication and Polymers. Soft lithography - micromolding, photo polymerization, Smart polymers and hydrogels, thick-film technologies. | |
5 | 3 | Lecture Topic 5: Microfluidic Principles Part I. Microfluidics lab-on-a-chip - silicon, glass and polymer material. | |
6 | 3 | Lecture Topic 6: Microfluidic Principles Part II. Electro-osmosis, electorphoresis, streaming potential, fluid dynamic principles. | |
7 | 2 | Midterm Exam (2 hours closed book on material covered in weeks 1-6) | |
8 | 3 | Lecture Topic 7: Sensor Principles and Microsensors. Thermal, mechanical, flow, magnetic and optical sensors. | |
9 | 3 | Lecture Topic 8: Microactuators and Drug Delivery. Applications, role of actuators, activation methods, drug delivery systems. | |
10 | 3 | Lecture Topic 9: Biosensors | |
11 | 3 | No Class - Easter Good Friday | |
12 | 3 | Lecture Topic 10: Packaging power and safety. System integration, RF safety, power transfer and data transmission, energy-harvesting. | |
13 | 3 | Project Presentations & Review |
Week | L/T/A | Description |
|---|---|---|
3-4 | 1 | Lab 1- Introduction to ConventorWare & design example. |
5-9 | 2 | Lab 2 - Electrostatic 2D micro-mirror design and simulation. |
10-12 | 3 | Lab 3 - Electro-thermal micro-gripper Simulation. |
Students are reminded that they are required to adhere to all relevant university policies found in their online course shell in D2L and/or on the Senate website
Refer to the Departmental FAQ page for furhter information on common questions.
You can submit an Academic Consideration Request when an extenuating circumstance has occurred that has significantly impacted your ability to fulfill an academic requirement. You may always visit the Senate website and select the blue radio button on the top right hand side entitled: Academic Consideration Request (ACR) to submit this request.
For Extenuating Circumstances, Policy 167: Academic Consideration allows for a once per semester ACR request without supporting documentation if the absence is less than 3 days in duration and is not for a final exam/final assessment. Absences more than 3 days in duration and those that involve a final exam/final assessment, require documentation. Students must notify their instructor once a request for academic consideration is submitted. See Senate Policy 167: Academic Consideration.
If a student is requesting accommodation due to a religious, Aboriginal and/or spiritual observance, they must submit their request via the online Academic Consideration Request (ACR) system within the first two weeks of the class or, for a final examination, within two weeks of the posting of the examination schedule. If the required absence occurs within the first two weeks of classes, or the dates are not known well in advance as they are linked to other conditions, these requests should be submitted with as much lead time as possible in advance of the required absence.
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Academic Accommodations (for students with disabilities) and Academic Consideration (for students faced with extenuating circumstances that can include short-term health issues) are governed by two different university policies. Learn more about Academic Accommodations versus Academic Consideration and how to access each.
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